He said in a statement issued on social media: “It has the meant the absolute world and more to be able to pull on the green jersey with honour, step out onto a football pitch – especially at the Aviva Stadium – to represent our great country, standing singing Amhran na bhFiann ready to go out into battle with your fellow countrymen.
“Nothing has ever come close. I gave absolutely everything I had of myself to ensure that I did the jersey, the fans and the country proud, and know that I never took it for granted each time. I hope that showed.
“It will be heartbreaking not to be involved beyond this year, but I feel now is the right time to step aside without any regrets.
“I lived my own and every young Irish footballer’s dream – and represented this country with pride.”
McClean’s absence from the squad was not the only one of note, with Liverpool goalkeeper Caoimhin Kelleher also missing after suffering a gash to his knee in training which required 12 stitches, while Sheffield United defender John Egan and Cardiff winger Callum O’Dowda are also unavailable because of injury.
However, Celtic winger Mikey Johnston and Cardiff forward Callum Robinson were included for the games against Greece in Dublin on Friday, October 13 and Gibraltar in Faro three days later.
Ireland’s hopes of qualification are all but over after Group B defeats by France and the Netherlands last month left them with just three points from a possible 15.
Squad: Gavin Bazunu (Southampton), Mark Travers (Stoke, on loan from Bournemouth), Max O’Leary (Bristol City), Matt Doherty (Wolves), Festy Ebosele (Udinese), Nathan Collins (Brentford), Shane Duffy (Norwich), Dara O’Shea (Burnley), Andrew Omobamidele (Nottingham Forest), Liam Scales (Celtic), Ryan Manning (Southampton), Josh Cullen (Burnley), Jayson Molumby (West Brom), Alan Browne (Preston), Will Smallbone (Southampton), Jason Knight (Bristol City), Jamie McGrath (Aberdeen), Mark Sykes (Bristol City), Evan Ferguson (Brighton), Adam Idah (Norwich), Aaron Connolly (Hull), Chiedozie Ogbene (Luton), Callum Robinson (Cardiff), Mikey Johnston (Celtic).